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The U.S. Food and Drug Administration has approved Contrave (naltrexone hydrochloride and bupropion hydrochloride extended-release tablets) as treatment option for chronic weight-loss in addition to a reduced-calorie diet and physical activity. Using two separate drugs to lose weight can be very effective you will find combinations as you're watching FDA now awaiting approval. When dealing with fat loss and the people who go through it you should err to the side of caution and let the FDA do its job and demand some study be done in order that the public recognizes the side effects and risks of the medications before we take them. Keep in mind that drug companies are in business to make money and that they would say everything to keep people on their own medications. Researchers found that participants investing in this drug to get a year, lost weight within a month and have kept the load off during the entire 56 weeks of the study. Contrave can be a combination from the drugs naltrexone and bupropion, which seems to reflect a new trend of weight-loss drugs which are made up of multiple active ingredient, that might make them more efficient and safer. Combo-pilling could be the newest fad or in addition to this the newest to come under scrutiny and thus it is just more publicly known although in the past, comb-pilling for weight reduction has been around since the eighties. The biggest reason that utilizing a combination of pills is becoming popular will be the fact that by right now there aren't any long term prescription weightloss pills that have been authorized by the FDA apart from orlistat. The truly disturbing part is always that doctors are prescribing these combinations of medications although some people might of the combinations are already rejected or have yet to be authorized by the FDA. Seizures certainly are a side effect with Contrave and really should not be taken in those with seizure disorders. The drug could also raise hypertension and pulse rate, and mustn't be used in those with a history of cardiac arrest or stroke in the earlier six months. Blood pressure and pulse should also be measured before commencing the drug and throughout therapy while using drug. The FDA also warned that Contrave can raise blood pressure levels and heart rate and must stop used in patients with uncontrolled high blood pressure, as well as by a person with heart-related and cerebrovascular (blood vessel dysfunction impacting mental performance) disease. Patients which has a history of heart attack or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded from your clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes which has a boxed warning to alert medical professionals and patients for the increased chance of suicidal thoughts and behaviors connected with antidepressant drugs. The warning also notes that serious neuropsychiatric events happen to be reported in patients taking bupropion for quitting smoking. --Participating in support groups that help the family from the addict recover (such as Al-Anon or Nar-Anon).