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The researchers believe anthocyanins -- the pigments that provides the fruit its dark red color -- may be responsible for PPAR activation. Unfortunately, these medications may also cause some unwanted effects, like water retention, swelling in the ankles, putting on weight, muscle weakness, and fatigue. It can be used as an anti-diabetic medication designed to help control blood sugar spikes in patients that suffer from Type 2 Diabetes. One of these negative effects included Actos bladder cancer. This is because of the fact that there have been no warning labels around the side effect that may brought on by the drug. For chronic conditions for example type 2 diabetes, or hypertension, generic types of popular drugs offer affordable choices for patients. The FDA did not release a safety communication regarding these risks until June 15, 2011, basing their decision while on an ongoing ten-year study of the serious side effects of Actos. It is recommended to have reasons for sugar including chocolates, orange juice or glucose gel handy to handle the signs of low blood glucose levels. Existing guidelines and package inserts may need to be revised to add these risk characteristics of TZDs. Specifically, doctors are given to watch for excessive, rapid extra weight, difficulty breathing, and edema after starting drug therapy. You may also download the proper execution and fax it to 1-800-FDA-0178. Takeda's failure to warn those taking Actos of potential bladder cancer or heart failure risks will unquestionably factor into the equation, as well as the extent with the damages you've suffered. Not only is Actos being pulled but also the drug Competact, that's manufactured from the same company. Some of these compounds help cellular matrix to recognize insulin and employ glucose for energy. Cancer and other negative effects have led the public to look into filing an Actos lawsuit. Understanding about Actos gives you a clearer picture from the Actos Lawsuit and Actos Lawsuit settlements. Is that to say the drug wasn't tested for a lot more than a year before approval. ) includes prescription drug coverage and preventive healthcare.