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  • On September 26, UCLA researcher reported the final results of a study, which indicated that Asians who are struggling with alcoholism may benefit especially from naltrexone, certainly one of three medications licensed by the U.S. Food and Drug Administration (FDA) for the treatment of alcoholism. Recent research has found that a gene variant may predict naltrexone treatment success for alcoholism. About 50% of patients of Asian descent have a particular mutation that creates them likely to benefit from naltrexone, compared with about 20% of Caucasians and much less than 5% of African Americans, said lead study author Lara Ray, an assistant professor of psychology and director of the UCLA Addictions Laboratory. The findings are available online ( in the journal Neuropsychopharmacology and will be published in an upcoming print edition in the journal. Using two separate drugs to shed weight can be very effective you'll find combinations while watching FDA now awaiting approval. When dealing with weight reduction and the individuals who go through it you need to err to the side of caution and permit the FDA do its job and demand some research be done so the public knows the side effects and risks of the medications before we drive them. Keep in mind that drug companies come in business to generate income and that they would say almost anything to keep people on his or her medications. Researchers discovered that participants taking this drug to get a year, dropped a few pounds within a month and have kept the body weight off through the entire 56 weeks in the study. Contrave is often a combination with the drugs naltrexone and bupropion, which usually reflect a brand new trend of weight-loss drugs that are made up of several active ingredient, that might make them far better and safer. Combo-pilling will be the newest fad or in addition to this the newest ahead under scrutiny and for that reason it is just more publicly known recently, comb-pilling to lose weight has been around since the eighties. The biggest reason that by using a combination of pills has become popular will be the fact that by right now there are not any long term prescription weightloss pills that have been approved by the FDA besides orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications and some of the combinations are already rejected or have yet to be authorized by the FDA. Seizures certainly are a side effect with Contrave and shouldn't be taken in people with seizure disorders. The drug may also raise blood pressure and heart rate, and must not be used in individuals with a history of cardiac arrest or stroke in the last six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy with all the drug. The FDA also warned that Contrave can raise hypertension and pulse rate and must not used in patients with uncontrolled high hypertension, and also by a person with heart-related and cerebrovascular (circulation system dysfunction impacting the brain) disease. Patients having a history of heart attack or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes with a boxed warning to alert health care professionals and patients for the increased risk of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for stopping smoking. Most of the combinations that are used to enhance weight loss involve an amphetamine and an antidepressant. Phentermine and Prozac are a popular combination which were around for some time, although it has been around stuffed to truly combine the 2 and try to get FDA approval to showcase it as a weight loss pill. Right there should raise some warning flags if the greedy pharmaceutical companies don't want to be involved in combining medications and selling them something must be wrong with all the combination. In fairness there is one fat loss combination pill which is in front of the FDA now Contrave?which couples naltrexone, utilized to treat alcohol and substance abuse, while using antidepressant bupropion (Wellbutrin, Zyban) it's been given the just do it to move forward by an FDA advisory committee, but by yet hasn't been approved.