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Contrave is looking very promising for the people seeking a diet plan pill that actually works. The U.S. Food and Drug Administration reviewed Contrave on December 7, and approved the drug 13-7, stating the advantage of the drug outweighs the risk of a possible increase in blood pressure. Using two separate drugs to shed pounds can be very effective you will find combinations in front of the FDA now awaiting approval. When dealing with fat loss and the people who go through it you ought to err assisting caution and allow FDA do its job and demand some study be done in order that the public knows the side effects and hazards of the medications before we bring them. Keep in mind that drug companies come in business to generate money and that they would say everything to keep people on the medications. Researchers discovered that participants using this drug to get a year, dropped excess weight within one month and have kept the weight off through the 56 weeks from the study. Contrave can be a combination with the drugs naltrexone and bupropion, which appears to reflect a new trend of weight-loss drugs which can be made up of several active ingredient, that might make them far better and safer. Combo-pilling is the newest fad or better yet the newest ahead under scrutiny and so it is just more publicly known in recent months, comb-pilling for losing weight has been around since the eighties. The biggest reason that employing a combination of pills has become popular may be the fact that by right now there are no long term prescription diet pills that have been licensed by the FDA apart from orlistat. The truly disturbing part is doctors are prescribing these combinations of medications although some people might of the combinations are already rejected or have yet to be authorized by the FDA. Seizures are a side effect with Contrave and shouldn't be taken in people with seizure disorders. The drug may also raise blood pressure and heartbeat, and must not be used in individuals with a history of cardiac arrest or stroke in the last six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy with all the drug. The FDA also warned that Contrave can raise blood pressure and heartbeat and must stop used in patients with uncontrolled high blood pressure level, along with by you are not heart-related and cerebrovascular (blood vessel dysfunction impacting the mind) disease. Patients with a history of cardiac event or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes which has a boxed warning to alert medical professionals and patients for the increased chance of suicidal thoughts and behaviors connected with antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for quitting smoking. "There were no signs of depression or suicidal thoughts in trial participants," said Fujioka.